Genetics
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Medicine in 15 Years: Gene Therapy, Replacement Organs and the Hospital in Your Living Room (2041)
Part 3 of the series “The Future of Medicine”: by 2041, tailor-made gene therapies, organs from pigs and treatment at home could…
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First in Humans: Cellular Rejuvenation by Gene Therapy Begins in the Eye
With ER-100, a gene therapy intended to epigenetically “reset” ageing nerve cells in the eye is being tested in humans for the…
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One Injection, Around 20 Per Cent Longer Life: FGF21 Gene Therapy Rejuvenates Old Mice
Researchers in Barcelona gave old mice a one-off gene therapy injected into the muscle that releases the metabolic hormone FGF21. On average,…
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Gene Editing Against Heart Attacks: One Infusion Lowers LDL Cholesterol by up to 62 Per Cent
With the base editor VERVE-102, Eli Lilly permanently switches off the cholesterol gene PCSK9 in the liver. New trial data show a…
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435 Million Dollars for Younger Liver Cells: NewLimit Bets on mRNA Reprogramming
The Californian start-up NewLimit has closed one of the largest funding rounds in the longevity sector. It aims to rejuvenate liver cells…
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Klotho as an mRNA Therapy: First Trial of the “Longevity Protein” in Healthy Adults
The start-up Klothea Bio is testing an mRNA therapy intended to raise blood levels of Klotho. The small trial is taking place…
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Rejuvenation in the Brain: Reprogramming Gene Therapy for Alzheimer’s Moves Closer
The start-up YouthBio Therapeutics wants to rejuvenate nerve cells epigenetically using Yamanaka factors. The FDA has judged the preclinical data sufficient for…
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Dogs Lead the Way: The First Longevity Drug and Gene Therapies for Older Dogs
The FDA has completed another review step for LOY-002, a tablet intended to extend the healthy life of older dogs. In parallel,…
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Paying for Anti-Ageing Gene Therapy Yourself: Why Experts Warn Against Unregulated Offers
In special economic zones such as Próspera in Honduras, gene therapies for muscle growth and “rejuvenation” are offered for large sums of…
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Lowering Cholesterol with Gene Scissors: CRISPR Therapy CTX310 Still Works After One Year
A single infusion that switches off the ANGPTL3 gene in the liver permanently lowers LDL cholesterol and triglycerides. The one-year data from…
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